Periodontology 2000, 21, 1999, 176196 munksgaard 1999 in. Gingival overgrowth is a common side effect of phenytoin, termed phenytoininduced gingival overgrowth pigo. The expression gingival hyperplasia abnormal increase in the number of normal cells in a normal arrangement in an organ or tissue. Gingival enlargements generalised pocket dentistry. The followup of 02 and 12 months after mucogingival surgery showed that the free gingival graft promoted periimplant health, hygiene, and patient comfort.
There are several causes of gingival enlargement and they can be grouped into four categories. Gingival overgrowth definition of gingival overgrowth by. Gingival hyperplasia causes and complications in children. Pgo may vary from mild to severe and does not seem to be dose dependant. Hereditary, druginduced, and idiopathic gingival overgrowth have been reported. Molecular aspects of druginduced gingival overgrowth. Hereditary gingival fibromatosis can occur as an isolated.
Gingival enlargement an overview sciencedirect topics. Surgical treatment of gingival overgrowth with 10 years of. Causes and complications of gingival overgrowth in children. In severe cases, the excess tissue may cover the crowns of the teeth, thus causing functional, esthetic, and periodontal problems, such as bone loss and bleeding, due to the presence of pseudopockets. The pharmacological agents mainly associated with gingival overgrowth are. Conflation of gingival overgrowth and schwannoma bmj. The lesion, provisionally diagnosed as idiopathic gingival. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Phtinduced gingival overgrowth pgo is more common in children than in adults and affects both males and females equally.
Gingival overgrowth is a welldocumented side effect of cyclosporine administration in both dogs and people 3,4,5,6,7,8. Cyclosporine imagine a bicycle see the round wheel of the bicycle the round wheel reminds you of the round gum gingival overgrowth. Gingival hyperplasia hypertrophy is a rather common condition. Hereditary gingival fibromatosis hgf, also known as idiopathic gingival hyperplasia, is a rare condition of gingival overgrowth. Druginduced gingival overgrowth occurs as a side effect of some systemic medications. A wide range of causes have been attributed to gingival overgrowth. Sep 16, 2015 gingival enlargement or gingival overgrowth, a common trait of gingival disease, is characterized by an increase in the size of gingiva. We hypothesized that csainduced gingival overgrowth can be controlled by the use of specific agents to induce apoptosis. Gingival overgrowth is a common side effect of phenytoin, termed. The most common causes of gingival overgrowth are calcium channel blockers, used to treat high blood pressure and phenytoin, and antiseizure medication used to treat epilepsy.
Treatment of gingival overgrowth in a child with bardet. Specifically, these epulides do not originate from the gingival surface and so do not simply represent an enlargement of the commonly inflamed interdental papilla. To determine whether amlodipine alters the fibrotic response, we investigated its effects on treated gingival fibroblast gene expression as compared with untreated cells. Druginduced gingival overgrowth definition many terms have been used to describe gingival overgrowth.
Gingival overgrowth in paediatric cardiac transplant. Although there have been several case reports, few studies have examined the prevalence of nifedipine, diltiazem, and amlodipine. The most common causes of gingival overgrowth are calcium. The prevalence of phenytoininduced gingival hyperplasia is estimated at 15% to 50% in patients taking the medication 1,2 figures 401 and 402. Associated gingival overgrowth ap pears to reach maximum severity 1218 months after initiating phenytoin treatment 1, 19, 90. To get the facts on exactly how to eliminate your uterine fibroids from the root 100% naturally and permanently and achieve lasting freedom from pcos related symptoms without spending your hardearned money on drugs and over the counters. The exact incidence of occurrence is unknown, but is thought to affect approximately 2%3% of canine patients treated for atopic dermatitis with the medication 3,9.
Gingival enlargement may also be associated with the administration of three different classes of drugs, all producing a similar response. Gingival enlargement or overgrowth go is a common complication of the anticonvulsant drug phenytoin pht. Gingival hyperplasia is an overgrowth of gum tissue around the teeth. Druginduced gingival overgrowth does not originate in the periodontium.
The purpose of the current study was to explore a nonsurgical method to manage csainduced gingival overgrowth. Gingival enlargement, also synonymous with the terms gingival hyperplasia or hypertrophy, is defined as an abnormal overgrowth of gingival tissues. Mar 25, 2020 a person with gingival overgrowth may have trouble chewing and keeping the teeth clean, as gum tissue grows between the teeth. There are several causes of gingival enlargement and they can be. This chapter aims to provide an overview of the causes, features and management of generalised gingival swellings, which involve the free andor. Free gingival graft was obtained from the palate and grafted on the buccal side of interforaminal area. Druginduced gingival overgrowth is frequently associated with three particular drugs. This paper presents a case of pigo hindering oral function and compromising oral hygiene and aesthetics, which was treated with a combination of nonsurgical and surgical periodontal therapies. While gingival overgrowth is commonly associated with calcineurin inhibitors, particularly cyclosporine, a recent study showed that the occurrence of gingival overgrowth declined from 56. Free gingival graft to increase keratinized mucosa after. Gingival enlargement or overgrowth is a common disease of gingiva. Calcium channel blockers have been found to be responsible for a benign adverse reaction, gingival enlargement or overgrowth.
One of the main drugs associated with go is the antiepileptic. Learn the shocking truth about uterine fibroids, drugs and surgeries. In patients receiving cyclosporine for more than 3 months. Nevertheless, the overgrowth involves the gingival margin with extension to the interdental papilla. Gingiva or gums surround the teeth and provide a seal around them.
Gingival hyperplasia is an enlargement or overgrowth of the gum tissue, also known as the gingiva, around the necks of the teeth. The effective and predictable management of gingival overgrowth requires correct diagnosis and consideration of aetiological factors, as discussed in part 1 bdj 2017. Gingival enlargement and its treatment authorstream. Go is characterized by the accumulation of extracellular matrix in gingival connective tissues, particularly collagenous components, with varying degrees of inflammation. A person with gingival overgrowth may have trouble chewing and keeping the teeth clean, as gum tissue grows between the teeth. In people, gingival overgrowth is a common complication of cyclosporine administration for. Veterinary sciences free fulltext medical management of. Since gingival overgrowth is a druginduced increase in extracellular matrix proteins, the treatment is based on discontinuing the offending medication if at preop view of the maxilla of a fiveyearold wheaton terrier with generalized idiopathic gingival hyperplasia. The lesion may involve the interproximal spaces, and become so extensive that the teeth are displaced and their crowns covered. Phenytoininduced gingival overgrowth pigo is a common complication of the continuous use of medications. Gingival overgrowth induced by drugs such as phenytoin, nifedipine, and cyclosporin develops due to an increase in the connective tissue extracellular matrix. Pertinent management depends on precisely diagnosing the origin of enlargement. Yag laser that unexpectedly showed complete healing with normalization of the gingiva, making unnecessary further surgical treatment for gingival volume reduction.
Gingival overgrowth is a serious side effect that accompanies the use of amlodipine. This case refers to a patient, female, who developed a large gingival enlargement that has a combined etiology. Figure 4 illustrates gingival overgrowth on a patient who has been taking phenytoin for several years. Surgical management of gingival overgrowth pocket dentistry. Gingival enlargement, also called gingival hyperplasia, is thickening or overgrowth of the gum tissues that surround the tooth. To report on a case of cyclosporine arelated gingival overgrowth go treated by conventional scaling and erbium. A case of a 19yearold male presenting with maxillary and mandibular chronic inflammatory gingival enlargement associated with prolonged orthodontic therapy is reported here. To get the facts on exactly how to eliminate your uterine fibroids from. Gingival overgrowth go is a side effect associated with some distinct classes of drugs, such as anticonvulsants, immunosuppressant, and calcium channel blockers. The causative factors may range from inflammation due to local factors to conditioned enlargement and neoplastic enlargements.
To provide a brief overview of the aetiology of gingival overgrowth, and describe the principles of and techniques for its surgical management. This article reports a case of bbs in a boy who presented. Healthy gingiva appears in coral pink color, but may contain. Go is evident in almost half of the patients receiving pht therapy. Chronic inflammatory gingival enlargement associated with. Phenytoininduced severe gingival overgrowth in a child. Jun 10, 2014 gingival overgrowth go is a known sideeffect of calcium channel blockers. Druginduced gingival overgrowth is a side effect associated with 3 types of drugs. Apr 10, 2015 causes and complications of gingival overgrowth in children. Gingival enlargement or gingival overgrowth is a common finding in clinical. Gingival enlargement or gingival overgrowth, a common trait of gingival disease, is characterized by an increase in the size of gingiva.
The authors describe a seminal case report of a 10yearold boy with enlarged gingivae in relation to his maxillary anterior teeth. Gingival hyperplasia is a medical condition in which the gums increase in size. However due to their varied presentations, the diagnosis of these entities becomes challenging for the clinician. Gingival overgrowth how is gingival overgrowth abbreviated.
The management of drug induced gingival overgrowth dr. Phenytoininduced gingival overgrowth management with. Jun, 2019 hereditary gingival fibromatosis hgf, also known as idiopathic gingival hyperplasia, is a rare condition of gingival overgrowth. To provide a brief overview of the aetiology of gingival overgrowth, and describe the principles of and techniques for its surgical. In some pathological conditions, gingivitis caused by plaque accumulation can be more severe, with the result of an overgrowth. Surgical management using free grafts and guided tissue regeneration. Prevalence of gingival overgrowth induced by antihypertensive. Tissue enlargement may progress to the point that the tissue obscures the teeth and may interfere with occlusion enlargement tissue appear firm fibrotic, pale pink and resilient, has little tendency to bleed, and has lobed surface appearance enlargement usually through out the mouth and appear more pronounced in the. Gingival enlargement is one of the frequent features of gingival diseases. The histological and immunohistochemical findings in one of the sections showed it to be characteristic of schwannoma while the other. Drug induced overgrowth commonly occurs following medications prescribed for non dental causes. Treating patients with druginduced gingival overgrowth. Looking for online definition of gingival pocket in the medical dictionary.
A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Jun 10, 2014 druginduced gingival enlargement gingival enlargement is a well known consequence of administration of drugs such as anticonvulsants immunosuppressants calcium channel blockers clinical features 1. It is an increase in the size of the gingival tissues and thus the term overgrowth is many times used in place of the term hyperplasia. Although overgrowth occurred progressively over the study period, it continued at a decreased rate during the second year.
Gingival overgrowth hereditary gingival fibromatosis. View the article pdf and any associated supplements and figures for a period of 48 hours. Since gingival overgrowth is a druginduced increase in extracellular matrix proteins, the treatment is based on discontinuing the offending medication if at preop view of the. Gingival hyperplasia treatment, symptoms, causes, pictures. Several conflicting theories have been proposed to explain the fibroblasts function in gingival overgrowth. Druginduced gingival overgrowth does not originate in the periodontium, but it occurs exclusively in periodontal tissues and is generally not of the same magnitude in other tissues.
The degree of thickening ranges from involvement of the interdental papillae alone to gingival. As gingival enlargement develops, it affects the normal oral hygiene. Studies of patients taking this anticonvulsant drug suggest that bacterial plaque is an important. Yag laser that unexpectedly showed complete healing with. Read on to learn the facts about the condition, what causes it and how it is. Conflation of gingival overgrowth and schwannoma bmj case. Veterinary sciences free fulltext medical management. The expression gingival hyperplasia abnormal increase in the number of normal cells in. Gingival enlargement and its treatment authorstream presentation. Gingival gum enlargement, also known as gingival hyperplasia or hypertrophy, is an abnormal overgrowth of gingival tissues. There are a number of causes for this condition, but its often a symptom of poor oral hygiene or a side effect of using.
There are several types available, which will be discussed further down but two of the most important ones are the one induced by. Gingival overgrowth is an uncommon adverse effect of cyclosporine administration in veterinary species. This study was conducted to determine the prevalence and risk factors for go in patients treated with calcium channel blockers. Aug 12, 2010 in some pathological conditions, gingivitis caused by plaque accumulation can be more severe, with the result of an overgrowth. The lesion, provisionally diagnosed as idiopathic gingival enlargement, was completely excised and divided into two sections. Nevertheless, the overgrowth involves the gingival margin. Gingiva overgrowth an overview sciencedirect topics. Painless, beadlike enlargement of the interdental papilla and extends to facial and lingual gingival margins 2.
Gingival enlargement definition of gingival enlargement. Phenytoininduced severe gingival overgrowth in a child bmj. Jan 17, 2015 surgical management of gingival overgrowth aim. There are several types available, which will be discussed further down but two of the most important ones are the one induced by different medication and the one. Gingival enlargements and localized gingival overgrowths. Effects of gingival overgrowth gingival overgrowth causes both physical and psychological distress. Healthy gingiva appears in coral pink color, but may contain melanin pigment. Druginduced gingival overgrowth is a sideeffect and unwanted outcome of systemic medication and is limited to gingival tissues. The present study investigated gingival overgrowth in 19 cardiac transplant patients aged 2 years 8 months to 16 years 3 months 1. This condition is also known as gingival overgrowth, hypertrophic gingivitis or gingival hypertrophy. This paper presents a case of pigo hindering oral function and compromising oral. Definition increase in size of gingiva or gingival overgrowth. Having read this chapter, the reader should be aware of the contemporary surgical techniques used for the surgical management of gingival. Gingival fibromatosis is a rare and heterogeneous group of disorders that develop as slowly progressive, local or diffuse enlargements within marginal and attached gingiva or interdental papilla.
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